Glenn J Lesser Selected Research

PT2385

1/2020	Attenuating hypoxia driven malignant behavior in glioblastoma with a novel hypoxia-inducible factor 2 alpha inhibitor.
1/2018	Hypoxia-inducible factor 2α: a novel target in gliomas.

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Glenn J Lesser Research Topics

Disease

29	Neoplasms (Cancer) 03/2022 - 01/2004
17	Brain Neoplasms (Brain Tumor) 03/2021 - 01/2004
16	Glioma (Gliomas) 01/2021 - 01/2004
15	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 01/2004
10	Breast Neoplasms (Breast Cancer) 10/2021 - 11/2006
4	Fatigue 02/2019 - 03/2013
4	Cognitive Dysfunction 02/2019 - 12/2014
3	Head and Neck Neoplasms (Head and Neck Cancer) 01/2022 - 01/2018
3	Thrombocytopenia (Thrombopenia) 01/2018 - 12/2004
3	Lung Neoplasms (Lung Cancer) 01/2016 - 11/2006
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 10/2021 - 02/2008
2	Hypoxia (Hypoxemia) 01/2020 - 01/2018
2	Chronic Disease (Chronic Diseases) 10/2015 - 03/2013
2	Astrocytoma (Pilocytic Astrocytoma) 05/2015 - 02/2008
2	Intracranial Hemorrhages (Intracranial Hemorrhage) 12/2012 - 12/2004
2	Lymphoma (Lymphomas) 05/2012 - 09/2004
2	Vitelliform Macular Dystrophy 08/2009 - 11/2005
1	Microsatellite Instability 10/2021
1	Neoplasm Metastasis (Metastasis) 10/2021
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 03/2021
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2020
1	Residual Neoplasm 10/2019
1	Pain (Aches) 01/2019
1	Hyperglycemia 01/2018
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2018
1	Neutropenia 01/2018
1	Obesity 01/2018
1	Wounds and Injuries (Trauma) 01/2018
1	Bradycardia 01/2017
1	Hypertension (High Blood Pressure) 01/2017

Drug/Important Bio-Agent (IBA)

14	Temozolomide (Temodar)FDA LinkGeneric 01/2021 - 02/2008
5	Biomarkers (Surrogate Marker)IBA 10/2021 - 12/2017
2	LactoferrinIBA 03/2022 - 09/2018
2	theasinensin AIBA 03/2022 - 09/2018
2	ErbB Receptors (EGF Receptor)IBA 06/2020 - 02/2008
2	PT2385IBA 01/2020 - 01/2018
2	VaccinesIBA 10/2019 - 02/2008
2	Biological ProductsIBA 01/2019 - 03/2017
2	Influenza Vaccines (Influenza Vaccine)FDA Link 08/2018 - 12/2014
2	coenzyme Q10 (CoQ10)IBA 01/2018 - 03/2013
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2018 - 01/2017
2	Transcription Factors (Transcription Factor)IBA 01/2018 - 01/2018
2	Vitamin E FDA LinkGeneric 01/2018 - 03/2013
2	Vorinostat FDA Link 01/2018 - 06/2015
2	Tyrosine Kinase InhibitorsIBA 01/2017 - 02/2008
2	Bevacizumab (Avastin)FDA Link 10/2015 - 01/2015
2	Pharmaceutical PreparationsIBA 10/2015 - 12/2013
2	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 12/2012 - 12/2004
1	Antineoplastic Agents (Antineoplastics)IBA 10/2021
1	pembrolizumabIBA 10/2021
1	APOBEC-1 DeaminaseIBA 10/2021
1	B7-H1 AntigenIBA 10/2021
1	Immune Checkpoint InhibitorsIBA 10/2021
1	Peptides (Polypeptides)IBA 10/2021
1	atezolizumabIBA 10/2021
1	Topotecan (Hycamtin)FDA LinkGeneric 03/2021
1	Topoisomerase InhibitorsIBA 03/2021
1	EnzymesIBA 01/2021
1	2,2- dimethyl- N- (6- oxo- 6,7- dihydro- 5H- dibenzo(b,d)azepin- 7- yl)- N'- (2,2,3,3,3- pentafluoropropyl)malonamideIBA 01/2021
1	osimertinibIBA 06/2020
1	epidermal growth factor receptor VIIIIBA 06/2020
1	endothelial PAS domain-containing protein 1IBA 01/2020
1	taxaneIBA 01/2020
1	Pioglitazone (Actos)FDA Link 02/2019
1	Odorant Receptors (Odorant Receptor)IBA 01/2019
1	Donepezil (Aricept)FDA LinkGeneric 01/2019
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2019
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2019
1	MethyltransferasesIBA 10/2018
1	TabletsIBA 09/2018
1	Amylases FDA Link 09/2018
1	C-Reactive ProteinIBA 01/2018
1	Complement System Proteins (Complement)IBA 01/2018
1	RNA (Ribonucleic Acid)IBA 01/2018
1	alovudineIBA 03/2017
1	T-Type Calcium Channels (T-Type Calcium Channel)IBA 01/2017
1	fms-Like Tyrosine Kinase 3IBA 01/2017
1	MibefradilIBA 01/2017
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2017
1	tandutinibIBA 01/2017
1	Alanine Transaminase (SGPT)IBA 01/2017
1	tyrosine receptor (receptor, tyrosine)IBA 01/2017
1	Phosphotransferases (Kinase)IBA 01/2017
1	Platelet-Derived Growth FactorIBA 01/2017
1	Modafinil (Provigil)FDA Link 10/2015

Therapy/Procedure

22	Radiotherapy 01/2022 - 01/2004
18	Therapeutics 03/2021 - 01/2004
11	Drug Therapy (Chemotherapy) 03/2022 - 08/2009
2	Aftercare (After-Treatment) 01/2021 - 03/2017
2	Salvage Therapy 05/2015 - 11/2005
2	Perioperative Period 12/2012 - 12/2004
2	Contraindications 12/2012 - 12/2004
1	Medical Day Care (Partial Hospitalization) 03/2020
1	Computer-Assisted Surgery (Image Guided Surgery) 03/2020
1	Chemoradiotherapy 01/2020
1	Adjuvant Radiotherapy 01/2019
1	Pain Management 01/2019
1	Immunotherapy 12/2017
1	Oral Administration 01/2017
1	Precision Medicine 01/2016